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          <given>Morenikeji A</given>
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    <title>Data for the research on &quot;Validation of Olive-Castor oil (OL-C) blend as a bio-membrane model&quot;</title>
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      <item>pharmacy</item>
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    <keywords>Lipophilicity; Validation; Octadecylsilane; Olive-Castor Oil; Retention behaviour; Biomimetic; Biomembrane; Permeability; 3401 Analytical chemistry; 321405 Pharmaceutical sciences</keywords>
    <abstract>This is the raw data for the research that validated the performance of Olive-Castor Oil (OL-C) vs. that of octadecylsilane (ODS) in bio-membrane simulation on a planar chromatographic platform by determining the retention characteristics of a number of opiods with similar pharmacophore, using a methanol/water binary mixture of varying compositions as mobile phase on the two platforms. The rationale was that the OL-C model was previously reported as possessing a fairly complex architecture compared to routinely used models like octadecylsilane (ODS).</abstract>
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      <item>Adeyemo, Morenikeji A.</item>
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      <item>Idowu, Sunday O.</item>
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    <collection_method>Lipophilicity was evaluated using reversed-phase thin layer chromatographic procedure on silica gel plate. The retention characteristics of some opiods with similar pharmacophore were determined using a methanol/water binary mixture of varying compositions as mobile phase on OL-C and ODS platforms. In vivo biological parameters were computed with the preADMET software. The degree of agreement in lipophilicity measurements by the two biomembrane models (OL-C and ODS) was determined by the Bland-Altman plot.</collection_method>
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